P03-021 - Characterization of BM-MSC from osteopetrotic mice
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چکیده
منابع مشابه
P03-021 - Characterization of BM-MSC from osteopetrotic mice
Introduction Autosomal Recessive Osteopetrosis (ARO) is a severe bone disease characterized by increased bone density due to impairment in osteoclast bone resorptive function (osteoclast-rich forms) or differentiation (osteoclast-poor forms). The latter form carries mutations in Tnfsf11 gene, which codifies for the receptor activator of NFB ligand (RANKL), an essential cytokine expressed in str...
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Changes in structure, cellularity, hematopoietic progenitor cell and macrophage content, and osteoclast activity were investigated in the hematopoietic organs of the colony-stimulating factor 1(CSF-1)-less osteopetrotic (op/op) mouse. The data indicated that op/op mice undergo an age-related hematopoietic recovery and resolution of osteopetrosis, suggesting that the hematopoietic system has the...
متن کاملDelayed Hematopoietic Development in Osteopetrotic ( op / op ) Mice By Susan
Changes in structure, cellularity, hematopoietic progenitor cell and macrophage content, and osteoclast activity were investigated in the hematopoietic organs of the colony-stimulating factor l(CSF-1)-less osteopetrotic (op/op) mouse. The data indicated that op/op mice undergo an agerelated hematopoietic recovery and resolution of osteopetrosis, suggesting that the hematopoietic system has the ...
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ژورنال
عنوان ژورنال: Pediatric Rheumatology
سال: 2013
ISSN: 1546-0096
DOI: 10.1186/1546-0096-11-s1-a219